For people with cancer, leukemia, and other serious blood diseases, bone marrow transplant is often the last hope for lack of medication or effective therapy. In fact, it is a question of replacing the defective blood cell factory with that of a donor to start from scratch. A cumbersome process, which takes time, and often causes complications. In 50 to 60% of cases, transplant patients have their grafts turned against them. This is called graft disease versus the other. The result is attacks of the skin, liver … and death in 10% of cases.

In total, approximately 1,000 patients are affected each year in France. What situate pathology in the context of rare diseases, hence the difficulty of having sufficient data to analyze and understand this phenomenon. To make up for this lack, two doctors, Boris Calmels from the Paoli-Calmettes Institute in Marseille, and Régis Peffault de Latour from the Saint-Louis Hospital in Paris, created Cryostem. The goal is twofold: to establish a biological collection with patients before and after the transplant and to make this collection available for research.

A cohort of 5,600 patients and 2,300 donors

<p class = "canvas-atom-canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "The project is selected as part of a call for national project, which earned him a starting funding of 5 million euros from 2011 to 2019. The first patient is integrated in 2012 and to date, the cohort groups the biological data of 5,600 patients, adults and children as well as 2,300 donors. "Our strength is our networking, observes Emilie Robert, project manager Cryostem. A network of 37 transplant units and 27 laboratories while "before, the doctors each had their collection in their corner"." data-reactid = "25"> The project is selected as part of a national call for projects, which earned it a starting funding of 5 million euros from 2011 to 2019. The first patient is integrated in 2012 and to date, the cohort groups biological data from 5,600 patients, adults and children, as well as 2,300 donors. "Our strength is our networking, observes Emilie Robert, project manager Cryostem. A network of 37 transplant units and 27 laboratories while "before, the doctors each had their collection in their corner".

<p class = "canvas-atom-canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = "Data that has been made available to researchers since 2015. "They are used for eight national projects and one project"data-reactid =" 26 "> Data that has been made available to researchers since 2015."They are used for eight national projects and one project

<p class = "canvas-atom-canvas-text Mb (1.0em) Mb (0) – sm Mt (0.8em) – sm" type = "text" content = " (…) Read more on La Tribune.fr "data-reactid =" 27 "> (…) Read more on La Tribune.fr